We explore what allosteric modulators are, their benefits and drawbacks, and which candidates are currently advancing through ...

Chemical sensors whose signals can be amplified by various triggers hold huge potential in multidisciplinary sciences. However, developing such systems was considered a highly challenging task, until ...

A multinational research team led by researchers at Institute of Science Tokyo, RIKEN, and the University of Toronto has ...

The new dynamic allosteric effector presents an effective alternative to conventional signal amplification and chemosensor systems. Disclaimer: AAAS and EurekAlert! are not responsible for the ...

Researchers at the Centre for Genomic Regulation and the Wellcome Sanger Institute have comprehensively identified the allosteric control sites found in the protein KRAS, which is one of the most ...