Antibiotic management of acute uncomplicated appendicitis among children was inferior to appendectomy, a randomized non-inferiority trial showed. For nearly 850 children with available primary outcome ...

Ten-year follow-up results showed that 37.8% of patients who received antibiotics versus appendectomy had a true recurrence of appendicitis. Overall, cumulative complication rates at 10 years were ...

We conducted a pragmatic, nonblinded, noninferiority, randomized trial comparing antibiotic therapy (10-day course) with appendectomy in patients with appendicitis at 25 U.S. centers. The primary ...

February 22, 2011 — For children with a perforated appendix, early appendectomy appears to reduce the time away from normal activities and has fewer adverse events vs another common option, the ...