Prostate cancer is initially androgen-dependent but, over time, usually develops hormone- and chemo-resistance. The present study investigated a role for p21-activated kinase 4 (PAK4) in prostate ...

Neural activity in healthy brain releases glutamate which binds to synaptic receptors and activates Ca ++ influx and further signaling pathways of CAM/ERK/MAPK/CREB in neurons. CREB elevation leads in ...

Scientists have designed and developed novel biosensors that allow the simultaneous study of both sensory evoked neuronal activity and transcription factor dynamics. Our brains have a remarkable knack ...

Luc Desfrere, Marie Karlsson, Hiromi Hiyoshi, Seth Malmersjö, Evanthia Nanou, Manuel Estrada, Ayako Miyakawa, Hugo Lagercrantz, Abdeljabbar El Manira, Mark Lal, Per ...

from Stratagene Signal transduction seems like such a simple concept: transmitting messages within and between cells. But when you consider the hundreds of genes that are involved in signal ...

Despite increasing evidence linking alcohol consumption to cancer, little is known about the biological mechanisms behind the association. Now, researchers at the University of Miami report that ...

Young blood really does rejuvenate the brain, at least in mice, raising hopes that molecules in the blood may be identified to do the same for humans, according to a study stemming from the ongoing ...

Our brains have a remarkable knack for adaptability. Each and every day the neuronal connections within are constantly changing, molded by what we experience in our daily lives. The memories we make, ...