T-cell redirection therapy using chimeric antigen receptor (CAR) T cells and/or bispecific antibody (BsAb) has been established and become a promising treatment strategy for relapsed/refractory B-cell ...
Radiation-induced bystander effect (RIBE) refers to a unique process, in which factors released by irradiated cells or tissues exert effects on other parts of the animal not exposed to radiation, ...
Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...
A CAR-T cell product can contain both CAR-T cells and CAR-negative bystander T cells (left). After treatment with CAR-T cell therapy, CAR-T cells kill tumor cells and release a panel of cytokines. In ...