Cells that double their entire genome do not all share the same fate. New research published in the Proceedings of the ...
In most known bacterial species, cell division starts with the formation of the cytokinetic ring, the Z-ring, at the cell’s middle 1,2. In Escherichia coli, the Z-ring consists of FtsZ protofilaments ...
Cells that acquire a doubled genome after a failed division step survive and proliferate far more effectively than cells left ...
Squamous or epidermoid cancer arises in stratified epithelia but also is frequent in the non-epidermoid epithelium of the lung by unclear mechanisms. A poorly studied mitotic checkpoint drives ...
For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...
Cell division is an essential process for all life on Earth, yet the exact mechanisms by which cells divide during early embryonic development have remained elusive—particularly for egg-laying species ...
A 'pocket' on the protein cyclin B is responsible for ensuring that the steps of cell division take place in the correct order. Cell division is key for life. Every organism -- from the smallest yeast ...
A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages ...