When cells are healthy, we don't expect them to suddenly change cell types. A skin cell on your hand won't naturally morph into a brain cell, and vice versa. That's thanks to epigenetic memory, which ...

An international research team led jointly by the University Medical Center Göttingen (UMG), the University of Göttingen and ...

Investigators led by Navdeep Chandel, Ph.D., the David W. Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care, have discovered how the metabolism of mitochondria supports ...

We then compared the phenotype of P14 T cells and examined expression of the memory T cell-associated molecule, CD127, along with a TE cell- and t-T EM cell/LLEC-associated molecule, KLRG1. Consistent ...

Scientists reprogram brain immune cells to fight Alzheimer's: Study ...

However, details of the intervening steps, as researchers have learned in the past 65 years, are quite complex — certain cells carry the flu antigen to the immune system, specific immune cells respond ...

For decades, dogma dictated that the immune system consisted of two separate branches. Cells of the innate system respond rapidly to molecular patterns shared by a broad array of pathogens. Meanwhile, ...

The Israeli study examined tumor samples and nearby lymph nodes from 11 patients with high-grade serous ovarian cancer.

T lymphocytes differentiate from naïve precursors upon antigen encounter into distinct effector and memory subsets. Following priming by antigen-presenting cells in lymphoid tissues, naïve CD4+ and ...

A new study uses optogenetics and roflumilast to prove sleep deprivation blocks memory retrieval, not storage.

A newly identified molecule called OLE helped restore the brain’s immune cells to a more protective state in Alzheimer’s ...