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Using live true single-circulating tumor cell comprehensive genomics to show clonal evolution and tumor heterogeneity in pancreatic cancer management.

AI-based predictive tool for detection of ctDNA in pancreatic adenocarcinoma using nationwide comprehensive genomic profiling data. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I ...
ascopubs.org

Molecular and clonal evolution of primary lesions vs brain metastasis of EGFR-mutated NSCLC: A retrospective cohort study.

Efficacy and safety of durvalumab plus tremelimumab versus standard chemotherapy for non-small cell lung cancer: A systematic review and meta-analysis of phase III randomized controlled trials. This ...
GEN

Mutation Mechanism Found That Drives the Aggressive Development and Evolution of Osteosarcoma

Researchers published a new study, “Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution,” in Cell that they say solves the mystery of what drives the genomic ...
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Tumor-Infiltrating Clonal Hematopoiesis Increased Risk of Poor Outcomes in Cancer

Tumor-infiltrating clonal hematopoiesis (TI-CH) increased the risk of disease recurrence or death among patients with early non-small cell lung cancer (NSCLC), and the risk of death from any cause ...