Real-time visualization of DNA wrapping around histone H2A using HS-AFMA DNA strand initially slides on histone H2A, then sequentially adopts Sandwiching and Wrapping topologies (scale bar: 30nm).
DNA strands wrap around histones, which are clustered into eight-histone balls that are threaded like beads on a string into fibers that are further intertwined to form chromosomes. Cells don’t store ...