Adults recovering from surgery now have access to a pain drug that works through an entirely different biological mechanism ...

Individuals with HIV who were resistant to all four antiretroviral drug classes experienced higher mortality than those who were not resistant, a difference primarily due to lower CD4 cell counts.

First-in-class drugs can be highly innovative because of their novel mechanisms of action, but they also carry uncertainty in the absence of clinical experience. To understand how such drugs advance ...

Add Yahoo as a preferred source to see more of our stories on Google. Nitazenes, like this powder sample, are a class of synthetic opioids more potent than morphine and fentanyl. Joe Lamberti/The ...

Hyperactive signaling pathways of some aggressive blood cancer cells can be tamped down by a previously unrecognized protein complex, ensuring the cancer's survival. If one component of the complex is ...

A research team at McMaster University has discovered a new drug class that could someday lead to breakthrough treatments for dangerous fungal infections. The new molecules, dubbed coniotins, were ...

The choice of which therapeutic alternatives to compare drugs against will be foundational in Medicare’s drug price negotiation, now and in future years. We believe a broad approach to the selection ...

A new experimental antibiotic can handily knock off one of the world’s most notoriously drug-resistant and deadly bacteria —in lab dishes and mice, at least. It does so with a never-before-seen method ...