A new study found that SSRIs may be able to help other drugs cross the blood-brain barrier. The findings could aid the delivery of drugs for conditions like dementia. The corresponding study was ...

Getting drugs to the brain is difficult. The very thing designed to protect the brain's environment — the blood-brain barrier (BBB), tightly packed cells that prevent most substances from passing ...

Drug delivery to the brain remains challenging mainly due to the blood-brain barrier (BBB) that regulates the entrance of substances to the brain.We use a Nanotechnology approach to enhance drug ...

"The blood-brain barrier prevents most drug uptake into the brain," Dr. Padmanabhan said. "Insights from this device will help inform ultrasound treatment protocols and establish a balance where ...

Antisense oligonucleotides (ASOs), which bind to RNA and prevent them from being translated into proteins, have gained popularity in recent years as a way to treat neurodegenerative diseases. However, ...

Toxoplasma gondii is a protozoan parasite famous for its cunning ways. This microbial manipulator can only reproduce inside of cats, so, if it finds itself in another mammalian host, like a rat, it ...

The properties of the blood-brain barrier serve a vital protective role, but they also keep drugs from reaching the organ. Big pharmaceutical companies have been making deals for technologies that ...

Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that ...

While this protects the brain from external threats, it also presents a major challenge for treating neurological diseases, as many potentially therapeutic compounds are unable to cross. One potential ...

Use of MRI-guided focused ultrasound with standard chemotherapy is safe and may improve outcomes for people with glioblastoma ...