A detailed quantitative model of signaling by IRE1 sheds light on the mechanism of its activation by endoplasmic reticulum stress and addresses a long-standing controversy in the field. In eukaryotes, ...

Scientists use math and physics to address the mystery of just how the endoplasmic reticulum, an organelle essential to life at the cellular level, continually re-arranges itself As a second-year Ph.D ...

Improvements in public health have allowed humankind to survive to older ages than ever before, but, for many people, these added golden years are not spent in good health. Aging is a natural part of ...