The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's ...

Sugars known as glycans form dense envelopes around cells. But they’re often ignored in biological investigations because, unlike DNA, proteins and other cellular components, tools to study them are ...

Researchers have identified a new function of a well-known enzyme: the signal peptidase complex is responsible for the quality control of membrane proteins. The discovery of this new function for a ...

University of Delaware biochemist Jeff Mugridge is trying to figure out how so-called mRNA eraser enzymes work in our cells, why those erasers can sometimes misbehave and lead to cancer, and how ...

Researchers at UT Arlington have discovered a key enzyme, IDO1, that when blocked, helps immune cells regain their ability to properly process cholesterol—something that breaks down during ...

An enzyme called MARK2 has been identified as a key stress-response switch in cells in a study by researchers at Johns Hopkins Bloomberg School of Public Health. Overactivation of this type of stress ...

New research from Johns Hopkins Medicine shows that the enzyme biliverdin reductase A (BVRA) plays a direct protective role against oxidative stress in neurons, independent of its role producing the ...

Recent findings from a preclinical study conducted by Weill Cornell Medicine researchers have uncovered a pivotal role of the enzyme PGK1 in brain cell energy production, offering new hope for ...

Researchers have discovered that an enzyme can serve as an ideal target for developing new therapeutics against Lyme disease, and most likely other tick-borne diseases as well. The finding was ...

An illustration of the pig enzyme ST3Gal1 (green) bound to its sugar ligand (yellow sticks). Binding interfaces contain green (carbon), red (oxygen), and blue (nitrogen) surfaces. Credit: University ...