Genetic variants that cause rare disorders may remain elusive even after expansive testing, such as exome sequencing. The diagnostic yield of genome sequencing, particularly after a negative ...

The most exclusive club in omics has admitted only genomics and transcriptomics, the beneficiaries of single-molecule sequencing technologies that are so powerful they enable highly refined ...

Next-generation sequencing (NGS) has been an invaluable tool to understand both health and disease in many different organisms. However, for the most part, genomes are static replications of the ...

Whether you’re interested in why a living system works as it does or the reasons it goes awry, proteins are a critical part of the molecular picture. The proteins circulating in a person’s plasma can ...

Two examples of the same molecule represented in sequence, image and graph formats are provided for direct comparison. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news ...

What is Third-Generation Sequencing? Third-generation sequencing, also known as long-read sequencing, refers to the latest advancements in DNA sequencing technologies that enable the analysis of ...

Some strange mathematical sequences are always whole numbers — until they’re not. The puzzling patterns have revealed ties to graph theory and prime numbers, awing mathematicians. Simple, yes, but ...