Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

On some level, biology is all about regulation, regulation, regulation. One way that our cells regulate their genes is through a process called alternative splicing, which entails the selective ...

In an important new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of ...

Discover the innovative TECHNO platform for full-length gene humanisation, enhancing models for human gene function.

A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled “A combination of differential expression and network connectivity analyses ...