Platelet transfusion is a cornerstone in the management of thrombocytopenia and the prevention of bleeding in a wide range of clinical settings, yet it is beset by complex immunological, technical and ...

Research has proven frozen blood platelets are safe and effective for use in critically injured patients—a breakthrough dramatically extending their shelf life for transfusions from one week to two ...

Platelet transfusion thresholds in according bleeding risk and the presence of bleeding. WHO = World Health Organization. “In practice, we see all too often [that] prophylactic transfusion of ...

Febrile responses to platelet transfusions are common but some can be life-threatening and the cause of these reactions is largely unknown. In June 23 Lancet, Richard Phipps and colleagues from ...

Myelodysplastic syndromes (MDS) can damage bone marrow, lowering red blood cells and platelets. Transfusions replace missing cells to manage anemia or thrombocytopenia. Up to 9 in 10 people with MDS ...

Severe thrombocytopenia can be very dangerous, even fatal, without treatment. Treatment depends on the underlying cause but can include medications, transfusions, and surgery. Severe thrombocytopenia ...

Studies have demonstrated increased morbidity and mortality with platelet transfusions in the neonatal period. Platelets are as important for host immunity and inflammation as for hemostasis.

When blood is donated, it is rarely used as whole blood. Instead, blood banks separate it into different components so that ...

The trend in hospitals and guidelines is to be increasingly cautious with blood transfusions. Due to side effects associated with blood transfusion and the increasing scarcity and costs of blood ...