I'm working on an NT 4.0 machine (SP 5) and it intermittently gets the "0x0000007B Inaccessible Boot Device" BSOD. I looked it up on Microsoft ( LINK) and it seems to point to a bad registry/driver or ...
A 7B is inaccessible boot device - after replacing your motherboard, your OS no longer knows what your disk controller is, because it's not the same one from before the replacement.