Researchers at University College London have identified a molecular mechanism the human body uses to shut down acute ...

Inflammation is a natural reaction of the immune system, protecting and healing the body. Still, too much of it can lead to ...

System could enable study of complex biological processes in live animals over long periods with less tissue damage than ...

Chronic hepatitis B virus (HBV) infection remains a major cause of global liver morbidity, leading to progressive ...

A study led by the Innovation in Vesicles and Cells for Application in Therapy (IVECAT) group at the Germans Trias i Pujol Research Institute (IGTP) has identified a key mechanism regulating the ...

The results of the new study could have significant implications for understanding diabetes. Researchers from the University of Cologne have revealed a mechanism protecting pancreatic β-cells, which ...

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein ...

Osteoarthritis is increasingly recognised not merely as a wear-and-tear disorder but as a complex, low-grade inflammatory disease of the whole joint. Damage to cartilage matrix liberates endogenous ...

Cytokines are small secreted proteins that orchestrate immune and inflammatory responses by binding to specific receptors on target cells. Signalling through membrane-bound receptors typically ...

People with chronic kidney disease (CKD) have a significantly increased risk of death from cardiovascular disease. They also ...

Immunometabolism is an expanding field that examines the bidirectional interactions between immune signaling and metabolic regulation, with particular ...