Like poles support a tent, microtubules—hollow cylindrical structures made of tubulin protein—support eukaryotic cells. But microtubules provide more than just mechanical strength; they help prepare ...
Proteins containing disordered domains perform many important cellular functions. My lab currently has two main projects, one to dissect the role of tubulin's C-terminal tail in microtubule structure ...
Normally, Tau proteins stabilize microtubules and support neuronal function, but in neurodegenerative diseases such as ...