Researchers conducted a pioneering study to unravel the genetic programs triggered upon inflammation in microglia, specialized resident immune cells of the central nervous system. Using ...

A rare but potent genetic mutation that alters a protein in the brain’s immune cells, known as microglia, can give people as much as a three-fold greater risk of developing Alzheimer’s disease. A new ...

CAMBRIDGE, MA -- One of the hallmarks of Alzheimer’s disease is a reduction in the firing of some neurons in the brain, which contributes to the cognitive decline that patients experience. A new study ...

One of the hallmarks of Alzheimer's disease is a reduction in the firing of some neurons in the brain, which contributes to the cognitive decline that patients experience. A new study from MIT shows ...

WASHINGTON — When researchers at the University of Kentucky compare brains donated from people who died with dementia, very rarely do they find one that bears only Alzheimer’s trademark plaques and ...

They discovered this by comparing the motility of normal microglia with the microglia from MIA mice. The researchers also illuminated that in adolescence this altered process motility was linked to ...

Dementia has long been framed as a slow, irreversible loss of neurons, but a new line of research is shifting attention to the blood vessels that feed the brain. Scientists are now testing whether ...

A new study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer's pathology in other ways. A rare but potent genetic ...

(AP) — When researchers at the University of Kentucky compare brains donated from people who died with dementia, very rarely do they find one that bears only Alzheimer's trademark plaques and tangles ...

A new study by researchers in the Picower Institute for Learning and Memory at MIT demonstrates how a rare but potent genetic mutation that alters microglia, can give people as much as a three-fold ...