Christine Dunham is a leading expert on the ribosome—an elaborate macro-molecular machine that operates like a factory within a cell to manufacture proteins. "The ribosome is really the most ...

Transcription and translation are processes a cell uses to make all proteins the body needs to function from information stored in the sequence of bases in DNA. The four bases (C, A, T/U, and G in the ...

Proteoforms, the diverse molecular variants of proteins, are key to understanding cellular functions, disease mechanisms, and ...

A novel study uncovers how a subtle chemical tweak transforms the naturally occurring phytotoxin into a powerful molecular glue, 12-deoxyfusicoccin (12-dFC), that locks 14-3-3 proteins onto the ...

The protein factories in our cells – so-called ribosomes – have a central task: during a process known as translation, amino acids are linked together according to messenger RNA, forming a growing ...

The ribosome serves as the essential molecular machine that translates genetic information carried by messenger RNA (mRNA) into functional proteins. Comprised of two distinct subunits, the ribosome ...

A research team led by Prof. XU Zhiheng from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has identified Tapt1, together with its partner Suco, as important ...

Synthetic biologists from Yale were able to re-write the genetic code of an organism - a novel genomically recoded organism (GRO) with one stop codon - using a cellular platform that they developed ...

Since the COVID-19 pandemic, mRNA vaccines have gained attention as a next-generation pharmaceutical technology. mRNA therapeutics work by delivering genetic instructions that enable cells to produce ...

Scientists have identified a critical breakdown in the cellular machinery that produces proteins in aging brains.