Adaptor protein (AP) complexes play central roles in intracellular vesicular trafficking by coupling cargo selection to ...

Clathrin-mediated endocytosis (CME) is an essential cellular process that mediates the internalisation of diverse plasma membrane components and extracellular cargo. This mechanism relies on the ...

For Amy Engevik, an epithelial cell biologist at the Medical University of South Carolina who studies cell function in the gastrointestinal tract, protein location matters more than abundance. She ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...

This illustration shows how the membrane trafficking protein VAMP72 gradually changed during plant evolution to give rise to VAMP727, which functions in transporting storage proteins to vacuoles. The ...