The regulation of neuronal excitability and the maintenance of an appropriate balance between excitation and inhibition are central to brain function. Inhibitory synaptic transmission, predominantly ...

Researchers identify the Munc13-1 protein as a crucial molecular pathway for working memory, linking calcium signaling to ...

Working memory is a cognitive function that is essential for carrying out everyday activities and temporarily retaining ...

How do we think, feel, remember, or move? It all depends on transmission of chemical signals in the brain, carried and released by molecular containers called vesicles. In a new study, researchers ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...

Working memory is a cognitive function that is essential for carrying out everyday activities and temporarily retaining information.

A study shows Munc13-1 regulates synaptic strengthening via calcium signaling, enabling efficient neurotransmission and ...

Researchers used positron emission tomography, or PET, brain imaging on 32 people with AUD and 29 controls. They found 11% lower synaptic density in the frontal cortex, striatum, and hippocampus of ...

A new study by Pitt researchers challenges a decades-old assumption in neuroscience by showing that the brain uses distinct transmission sites—not a shared site—to achieve different types of ...