Tuberous sclerosis complex (TSC) is an autosomal dominant disease characterized by the presence of benign tumors called hamartomas, which can affect virtually every organ system of the body, including ...
Tuberous sclerosis complex (TSC)1 and TSC2 are tumor suppressors that inhibit cell growth and mutation of either gene causes benign tumors in multiple tissues. The TSC1 and TSC2 gene products form a ...