New research from Washington University School of Medicine in St. Louis suggests that transposable elements in various cancers potentially may be used to harness novel immunotherapies against tumors ...
Sankey diagram illustrating the inferred functions of TE-proximal genes. The width of connections between each vertical block represents the gene count, delineating GO term classifications associated ...
Regarded historically as genomic parasites, transposable elements (TEs) have now been recognized as significant contributors to cellular identity and function, especially in immune regulation.
Heterochromatin, sometimes known as the “dark side of the genome,” is a poorly studied fraction of DNA that makes up about half of our genetic material. For more than 50 years scientists have puzzled ...
New research suggests that transposable elements—or so-called “jumping genes”—may help scientists identify tumor-targeting proteins. The study, published Monday (March 27) in Nature Genetics, suggests ...
Around 2015, Katherine Chiappinelli was investigating the mechanism behind a group of drugs approved to treat blood cancers—and showing promise against other cancers—when she made a puzzling discovery ...
Researchers from the University of New South Wales (UNSW) Sydney report they have discovered that a particular transposable element in the genome has an effect on the immune response to virus ...
Researchers from UNSW Sydney have discovered that a particular transposable element, or jumping gene, in the genome has a profound effect on the immune response to virus infection. The findings in ...
The viral transposable element, MERVL, acts as a central switch during early embryonic development, driving totipotent gene programs. The findings clarify how ancient viral DNA shapes development and ...
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