Primary lateral sclerosis (PLS) is a motor neuron disease variation of ALS (amyotrophic lateral sclerosis) but far more rare. PLS refers to patients who seem to have disruptions with only upper motor ...

ALS progressively destroys the motor neurons that control voluntary muscles. Upper motor neurons, located in the brain, send messages to lower motor neurons in the spinal cord and from there to ...

Amyotrophic lateral sclerosis (ALS) is a degenerative neurological disorder that involves the death of nerve cells in the brain and spinal cord. This, over time, leads to the brain losing its ability ...

Scientists have identified the first compound that eliminates the ongoing degeneration of upper motor neurons that become diseased and are a key contributor to ALS (amyotrophic lateral sclerosis), a ...

Motor neuron disease (MND) is a progressive condition that occurs when certain nerve cells degenerate and die. There are two types of motor neuron cells. The upper motor neuron begins in the brain and ...

Primary lateral sclerosis (PLS) is a rare neurological disorder. It may take several years for a doctor to diagnose PLS. While there’s no cure, treatments can help improve quality of life. Primary ...

QRL-101, an oral small molecule being developed by QurAlis, was safe and reduced nerve-cell overactivity in ALS patients in ...

While a gradual loss in muscle strength is a natural part of aging, for many older adults it's more than just feeling a little weaker. Sarcopenia—a condition affecting nearly half of adults over ...

New compound targets neurons that initiate voluntary movement After 60 days of treatment, diseased brain cells look like healthy cells More research needed before clinical trial can be initiated ...