Two-dimensional polyacrylamide gel electrophoresis (2D gel electrophoresis) is one of the earliest high-resolution proteomics techniques used for visualizing and separating complex protein mixtures.

The analytical workflow begins with the separation of the complex protein mixture, often utilizing liquid chromatography (LC) or capillary electrophoresis (CE) coupled directly to the MS system.

Matthias Trost (left) is a Professor at Newcastle University (UK) with a lab comprising three focuses: method development for proteomics, the application of mass spectrometry in drug discovery and the ...

Despite significant advancements in medical science, cancer remains one of the most challenging diseases to diagnose and treat effectively. This challenge comes from a complex, multimodal molecular ...

'Spatial proteomics' methods take chemical snapshots of tissues and cells while retaining spatial information about where the materials come from. Some methods are based on microscopy, others on mass ...

Among proteomics techniques, protein microarrays may be getting a lot of buzz these days, but two-dimensional gels still do most of the work. That's because protein arrays present a number of ...

Protein biomarker discovery, validation and utilization require technologies that deliver proteome insights with breadth and depth. Liquid chromatography mass spectrometry (LC-MS), the gold-standard ...

Single-cell and spatial techniques have evolved in leaps and bounds over the last decade, spreading from genomics into each omic realm. The latest developments for spatial techniques in the proteomics ...

Evosep, a global leader in proteomics solutions, is proud to announce its relocation to new headquarters in Odense. This move will significantly enhance the company's ability to advance the use of ...