A first-in-class monoclonal antibody has shown significant reductions in skin disease in patients with cutaneous lupus erythematosus (CLE). Litifilimab met the primary endpoint of reduction of disease ...

Type I interferons are a family of cytokines that play a critical role in the immune system, particularly in antiviral defence and immunomodulation. In systemic lupus erythematosus (SLE), an ...

In a recent study published in Science Immunology, researchers investigated whether individuals with breakthrough infections of severe coronavirus disease 2019 (COVID-19) pneumonia demonstrated normal ...

Researchers have discovered that Type I interferon (IFN) plays a key role in helping the immune system effectively target viruses, while stopping white blood cells from 'going rogue' and attacking the ...

Alzheimer's disease (AD), the most common type of dementia, progressively impairs memory, concentration and the ability to learn new things and accomplish everyday activities. Although scientists do ...

Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone formation in the spine, leading to severe neurological symptoms due to spinal ...

The results of a new longitudinal analysis cast doubt on the utility of serial interferon assessment. Baseline evaluation of interferon (IFN)-stimulated genes (ISGs) may be a useful tool for assessing ...

ATLANTA – In their continuing work to limit the impact of COVID-19, Emory University researchers have, for the first time in nonhuman primates, studied how modulating the signaling of type 1 ...