Pharmacodynamic interactions alter pharmacologic efficacy of a drug, although drug plasma levels remain unaltered. 2 This has an impact on either the pharmacologic efficacy or on the magnitude of side ...
PURPOSE: To establish the safety and tolerability of ZD1839 (Iressa), a selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, and to explore its pharmacokinetic and ...
Purpose: The mechanisms for drug interactions with smoking and clinically significant pharmacokinetic and pharmacodynamic drug interactions with smoking are reviewed. Summary: Polycyclic aromatic ...
Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. An international team of ...
SAN JOSE, Calif., Dec. 14, 2023 (GLOBE NEWSWIRE) -- Rani Therapeutics Holdings, Inc. (“Rani Therapeutics” or “Rani”) (Nasdaq: RANI), a clinical-stage biotherapeutics company focused on the oral ...
AM-710 is an ultra-long-acting prodrug of orforglipron, with >150-fold half-life extension, enabling once every 3 month and once every 6 month dosing or longer A single subcutaneous dose of AM-710 ...
The platelet integrin receptor α IIb β 3 (GPIIb/IIIa) plays a critical role in thrombosis and hemostasis by mediating interactions between platelets and several ligands, primarily fibrinogen. [72] ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results