Yeast cells are widely used to study G protein-coupled receptors (GPCRs), a large group of cell surface proteins in humans. However, several of these proteins lose their function when introduced into ...

Membrane proteins are proteins that are part of or interact with cell membranes, and they are responsible for carrying out the majority of the functions of these membranes. Membrane proteins account ...

Clumps and tangles of tau protein are associated with Alzheimer's disease and other dementias, but tau protein also plays a role in healthy nerve cells. Healthy tau can assemble into an envelope ...

Proteins perform a vast array of functions in the cell of every living organism with critical roles in biological processes. There are numerous chemical switches that control the structure and the ...

Much of our understanding of proteins in general is relative to their function in the human diet. To be sure, one of the major functions of protein in the human body is to provide the structural ...

In a recent study published in the journal Nature Machine Intelligence, researchers developed "DeepGO-SE," a method to predict gene ontology (GO) functions from protein sequences using a large, ...

Researchers have discovered how unstructured segments of surface proteins regulate the biological function of a cell. Their study, published in Nature Communications, sheds new light on the interplay ...

New research from Dana-Farber Cancer Institute researcher Cigall Kadoch, PhD, along with colleagues at Princeton University and the Washington University in St. Louis, reveals a key role for ...

At least 40 proteins are required for the assembly and function of AMPA receptors, the main neurotransmitter receptors in excitatory synapses of the brain. In the past ten years, Fakler’s research ...