The San Francisco 49ers have been decimated by injuries all year, specifically at the running back position. Christian ...

In a season marred with injuries and filled with disappointing results, the San Francisco 49ers finally got some good news on Thursday. San Francisco has been ...

Questionable along with Bosa, Greenlaw and Guerendo is defensive tackle Khalil Davis, who has a knee injury. Linebackers ...

You might not think a one-yard Brock Purdy run would be the play of the season. But a quest for more info took us everywhere ...

With San Francisco 49ers running back Christian McCaffrey dealing with Achilles tendinitis to begin the year, Jordan Mason ...

Alisyn Camerota Announces CNN Exit After 10 Years A huge Buddha statue appeared by a road in New Jersey. Then the worshippers ...

With both McCaffrey and Jordan Mason on injured reserve as the 49ers head down the stretch, they turned to rookie Isaac ...

Rookie running back Isaac Guerendo left late in the fourth quarter of the 49ers' 38-13 win over the Chicago Bears with what most likley is a high ankle ...

San Francisco 49ers head coach Kyle Shanahan provided injury updates following Sunday's 38-13 victory over the Chicago Bears.

Watch San Francisco 49ers tight end George Kittle's Week 14 highlights as he caught six passes for 151 yards against the ...

San Francisco 49ers TE George Kittle slips through a crease for a 33-yard burst up the sideline. Watch highlights from San Francisco 49ers wide receiver Jauan Jennings in Week 14 as he caught seven ...

The 49ers have lost both of their top running backs to injuries. So how who will replace Christian McCaffrey and Jordan Mason ...