The Buffalo Bills (10-2) came into Sunday’s game against the San Francisco 49ers (5-7) looking to clinch the AFC East for the ...

Receiver Amari Cooper hauled in a one-handed catch while multiple Niners defenders wrapped around him when he pitched the ...

Looking at Sunday’s Buffalo Bills at LA Rams Week 14 NFL odds, lines and trends. Here’s what you need to know.

In a 35-10 win over the San Francisco 49ers at home in Orchard Park, HC Sean McDermott’s record coming out of the bye week remained perfect and the Buffalo Bills looked the part of a playoff contender ...

Another AFC East title has been locked up by the Buffalo Bills. The Bills (10-2) beat the San Francisco 49ers (5-7) in their ...

Bills quarterback Josh Allen and head coach Sean McDermott let loose after their win over the 49ers. The Bills (10-2) took a ...

What a day for Josh Allen. The Bills quarterback led his team to a 35-10 win over the 49ers in Week 13. Not only did he wrap ...

ORCHARD PARK, NEW YORK – DECEMBER 01: Mack Hollins #13 of the Buffalo Bills celebrates after scoring a touchdown in the ...

The Bills found the end zone in the snow against the 49ers thanks to the longest rush of James Cook’s career. Cook put his ...

Here are the full game day inactive lists for both the Buffalo Bills and San Francisco 49ers ahead of their Week 13 matchup ...

The Bills went down 3-0 early against the 49ers thanks to a field goal from kicker Jake Moody in a winter wonderland in ...

Snow has continued to fall around Orchard Park ahead of Week 13’s “Sunday Night Football” feature between the Buffalo Bills ...