This study provides valuable insights into the differential impact of intrinsic and synaptic conductances on circuit robustness, emphasizing intrinsic plasticity as a crucial but often overlooked ...

The function of human airway macrophages can be therapeutically manipulated by targeting cellular metabolism to support immunity in the lung, aiding the design of innovative strategies in respiratory ...

This work presents a valuable exploration of AI-assisted protein engineering, particularly in designing a VHH antibody with enhanced resistance and stability to extreme environments. However, the ...

This valuable study proposes a novel rapid-entry mechanism of S. aureus that involves the rapid release of calcium from lysosomes. The strength of the paper lies in a very interesting hypothesis; what ...

This manuscript describes a novel magnetic steering technique to target human adipose derived mesenchymal stem cells (hAMSC) or induce pluripotent stem cells to the TM (iPSC-TM). The authors ...

Experimental schematic and design. A) Schematic of magnetically-steered cell delivery to the TM. As cells are injected into the anterior chamber at a low flow rate, the experimenter places the “point ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, and public reviews. This manuscript describes a novel magnetic steering technique ...

Tumor Virus RNA Biology Section, HIV Dynamics and Replication Program, CCR/NCI/NIH, Bethesda, USA Collaborative Bioinformatics Resource, CCR/NCI/NIH, Bethesda, USA NCI RAS Initiative, Cancer Research ...

Combining electrophysiological, anatomical and functional brain maps reveals networks of beta neural activity that align with dopamine uptake.

During rest and sleep, memory traces replay in the brain. The dialogue between brain regions during replay is thought to stabilize labile memory traces for long-term storage. However, because replay ...