NEW YORK (AP) — Juan Soto, Blake Snell and Clay Holmes debut for new teams, Paul Skenes makes his first opening-day start at age 22 and Sandy Alcántara returns from Tommy John surgery.

A week after the defending champion Los Angeles Dodgers swept an opening two-game series over the Chicago Cubs in Tokyo, 26 other teams get underway Thursday on opening day in the U.S. and Canada.