In a new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A ...

Researchers from Carnegie Mellon University have discovered a way to target RNA that could lead to new treatment options for myotonic dystrophy type 1 (DM1), the most common adult-onset form of ...

Osaka, Japan – Changes in genes have been linked to the development of different diseases for a while. However, it's not ...

A research team at The University of Osaka revealed that the loss of heterochromatin can cause a chain reaction leading to ...

Pancreatic ductal adenocarcinoma (PDAC) is the most lethal form of pancreas cancer. It's also the most common form of the ...

Researchers at CSH Laboratory identified an oncogenic SRSF1–AURKA–MYC circuit driving pancreatic ductal adenocarcinoma.

It was 2012 when Love Dalén, a paleogeneticist at Stockholm University, first laid eyes upon a special specimen on a lab table in eastern Siberia. "Our Russian collaborators said, 'Come here into this ...

In 2010 Yukaghir hunters found the nearly intact carcass of a young woolly mammoth frozen in the northern Siberian permafrost. With its reddish-brown fur still clinging to its skin, the dog-sized calf ...

In TDP-43 proteinopathies, such as frontotemporal dementia, amyotrophic lateral sclerosis, and limbic predominant age-related TDP-43 encephalopathy, the notorious RNA binding protein abandons its post ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

Preclinical data demonstrates that Shape’s engineered AAV5 variant, SHP-DB1, efficiently targets the NHP brain after intravenous injection and transduces >95% of neurons in the Parkinson's ...