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  1. Secondary Progressive Multiple Sclerosis | National MS Society

    Some people with RRMS can develop secondary progressive MS, where neurological function steadily declines. Learn about SPMS symptoms, diagnosis and treatment.

  2. Secondary Progressive MS (SPMS): What It Is & Symptoms

    Jul 30, 2025 · Secondary progressive MS (SPMS) is a stage that comes after relapsing-remitting MS. Symptoms steadily get worse without clear breaks. You might have trouble walking, feel …

  3. What Is Secondary Progressive Multiple Sclerosis? - WebMD

    Oct 21, 2025 · Learn what it means if you enter secondary progressive multiple sclerosis, and find out how your symptoms differ from relapsing-remitting multiple sclerosis (RRMS).

  4. What Is Secondary Progressive MS? (SPMS) | MS Society

    Secondary progressive MS (SPMS) is a stage of MS which comes after relapsing remitting MS for many people. With this type of MS your symptoms or disability steadily ‘progress’, meaning …

  5. Secondary progressive multiple sclerosis (SPMS)

    Dec 22, 2025 · Secondary progressive multiple sclerosis (SPMS) is an advanced stage of the disease, marked by symptom worsening even without relapses.

  6. Secondary Progressive MS (SPMS) - Brigham and Women's …

    SPMS is a progressive, degenerative form of MS that develops in many people with RRMS. Learn about secondary progressive MS treatment, symptoms, and more.

  7. Secondary Progressive MS (SPMS)

    Secondary Progressive Multiple Sclerosis (SPMS) is diagnosed when a person with Relapsing-Remitting MS (RRMS) begins to experience a gradual worsening of neurological function over …

  8. Secondary-Progressive Multiple Sclerosis - Cedars-Sinai

    Secondary-progressive multiple sclerosis (SPMS) is the form of the disease that develops from relapsing-remitting multiple sclerosis (RRMS) . The MS disease course varies across …

  9. Secondary Progressive MS (SPMS): Symptoms, Causes, More

    Secondary Progressive MS is one of several forms MS can take. Learn more about its causes, progression, treatment, and more.

  10. Secondary Progressive MS: Symptoms, Treatments, and Causes

    Jul 22, 2025 · What Is Secondary Progressive MS? Everything to Know. Secondary progressive multiple sclerosis (SPMS) is when multiple sclerosis (MS) symptoms gradually worsen over …