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  1. Telomerase - Wikipedia

    Telomerase, also called terminal transferase, [1] is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres. A telomere is a region of repetitive sequences …

  2. Telomerase | Description, Function, & Facts | Britannica

    Nov 21, 2025 · Telomerase is an enzyme that influences cell life span by adding organic compounds known as nucleotides to telomeres, segments of DNA located at the ends of chromosomes.

  3. Biochemistry, Telomere And Telomerase - StatPearls - NCBI Bookshelf

    Dec 11, 2022 · Telomerase is a ribonucleoprotein structure comprising a functional RNA component and a catalytic reverse transcriptase component. The RNA component houses a template for the …

  4. Telomeres and Telomerase: Structure and Functions - Microbe Notes

    Mar 30, 2025 · In eukaryotes, telomerase, a telomeric enzyme includes a catalytic protein subunit known as telomerase reverse transcriptase (hTERT) and a core RNA component (hTR) that synthesizes …

  5. Definition of telomerase - NCI Dictionary of Cancer Terms

    Each time a cell divides, the telomeres lose a small amount of DNA and become shorter. Over time, the chromosomes become damaged and the cells die. Telomerase helps keep this from happening. …

  6. What Is Telomerase Activity and Why Is It Important?

    Jul 29, 2025 · Telomerase is the enzyme that counteracts this shortening by adding new telomeric DNA sequences, thereby maintaining or extending telomere length. Telomerase is classified as a …

  7. Telomerase - an overview | ScienceDirect Topics

    Telomerase is a reverse transcriptase that adds repeats of a DNA sequence (TTAGGG) to the ends of chromosomes (telomeres) in mitotic cells, thus maintaining their length and preventing cell cycle …

  8. Composition and Function of Telomerase—A Polymerase Associated …

    In this review, we focus on the structure, composition and function of telomerases. In addition, we discuss the origin and phylogenetic divergence of this unique RNA-dependent DNA polymerase as a …

  9. Regulation of human telomerase in homeostasis and disease

    Apr 2, 2020 · Telomerase is a ribonucleoprotein complex, the catalytic core of which includes the telomerase reverse transcriptase (TERT) and the non-coding human telomerase RNA (hTR), which …

  10. Telomeres and Telomerase Explained: Definition, Examples, Practice ...

    Telomerase is an enzyme that adds repetitive nucleotide sequences to the 3' end of the lagging strand during DNA replication. It contains an RNA template, which it uses to extend the telomeres.